Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 2/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3730644 | 0.86 | NR1H2 (0.45) | CHRM2CHRM1CHRM3NR1H2KLK7 | |
| SCHEMBL3398097 | 0.82 | CHRM2 (0.37) | CHRM2CHRM1CHRM3NR1H2KLK7 | |
| SCHEMBL29405280 | 0.81 | CHRM2 (0.35) | CHRM2CHRM1CHRM3NR1H2KLK7 | |
| SCHEMBL22990239 | 0.80 | CHRM2 (0.44) | CHRM2CHRM1CHRM3NR1H2USP2 | |
| SCHEMBL29222219 | 0.80 | CHRM2 (0.44) | CHRM2CHRM1CHRM3NR1H2USP2 | |
| SCHEMBL26198255 | 0.80 | CHRM2 (0.44) | CHRM2CHRM1CHRM3NR1H2USP2 | |
| SCHEMBL23186706 | 0.80 | CHRM2 (0.44) | CHRM2CHRM1CHRM3NR1H2USP2 | |
| SCHEMBL18593025 | 0.80 | CHRM2 (0.44) | CHRM2CHRM1CHRM3NR1H2USP2 | |
| SCHEMBL16224801 | 0.79 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2KLK7 | |
| SCHEMBL7979086 | 0.79 | KLK7 (0.36) | CHRM2CHRM1CHRM3NR1H2KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643056-B1 | Process for the stereospecific preparation of 1,3-dioxan-4,6-dion derivatives, precursors of chiral tetramic acids derivatives | ISOCHEM SA (FR) | 2000-02-16 | — | — | EP | disclosed |
| US-5498732-A | REACTION WITH MELDRUM'S ACID | PROPEPTIDE (FR) | 1996-03-12 | — | — | US | disclosed |
| EP-0643056-A1 | Process for the stereospecific preparation of 1,3-dioxan-4,6-dion derivatives, precursors of chiral tetramic acids derivatives | PROPEPTIDE (FR) | 1995-03-15 | — | — | EP | disclosed |
| US-4978759-A | REACTING MELDRUM*S ACID WITH PROTECTED AMINO ACID, CYCLIZATION DECYCLIZING, REDUCTION AND DEPROTECTING; STATINE | SANOFI, S.A. AND INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1990-12-18 | — | — | US | disclosed |