Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963617 | 1.00 | KLK7 (0.36) | KLK7KLK5CHRM2CHRM1CHRM3 | |
| SCHEMBL8021097 | 0.79 | CHRM2 (0.42) | KLK7KLK5CHRM2CHRM1CHRM3 | |
| SCHEMBL5963373 | 0.76 | EPHX1 (0.37) | CHRM2CHRM1CHRM3NR1H2ALDH1A1 | |
| SCHEMBL5963831 | 0.76 | KLK7 (0.33) | KLK7KLK5PLA2G10PLA2G5ELANE | |
| SCHEMBL3398097 | 0.75 | CHRM2 (0.37) | KLK7KLK5CHRM2CHRM1CHRM3 | |
| SCHEMBL3324495 | 0.75 | KLK7 (0.36) | KLK7KLK5MMP3ADAM17USP2 | |
| SCHEMBL7132129 | 0.75 | KLK7 (0.36) | KLK7KLK5MMP3ADAM17USP2 | |
| SCHEMBL29405280 | 0.75 | CHRM2 (0.35) | KLK7KLK5CHRM2CHRM1CHRM3 | |
| SCHEMBL8549243 | 0.72 | KDM4E (0.32) | KLK7CHRM2CHRM1CHRM3USP2 | |
| SCHEMBL20734866 | 0.72 | KLK7 (0.36) | KLK7KLK5CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218553-B1 | METALLIZATION BY REACTING A BACCATIN III DERIVATIVE WITH A METAL ALKYLDISILAZIDE | THE STATE UNIVERSITY OF NEW YORK AT STONY BROOK | 2001-04-17 | — | — | US | disclosed |