Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 10/20 | 0.60 |
| ▸ | CASP1 | P29466 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018610 | 0.88 | CCR3 (0.57) | CCR3 | |
| SCHEMBL8014171 | 0.86 | CCR3 (0.66) | CCR3 | |
| SCHEMBL7608481 | 0.86 | CCR3 (0.66) | CCR3 | |
| SCHEMBL29447178 | 0.83 | CCR3 (0.62) | CCR3 | |
| SCHEMBL3930225 | 0.83 | CCR3 (0.62) | CCR3 | |
| SCHEMBL3930227 | 0.83 | CCR3 (0.62) | CCR3 | |
| SCHEMBL3926453 | 0.82 | CCR3 (0.59) | CCR3 | |
| SCHEMBL3926458 | 0.82 | CCR3 (0.59) | CCR3 | |
| SCHEMBL3935453 | 0.81 | CCR3 (0.67) | CCR3 | |
| SCHEMBL3935460 | 0.81 | CCR3 (0.67) | CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000053172-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-09-14 | — | — | WO | claimed |
| WO-2000053172-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-09-14 | — | — | WO | disclosed |