Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 3/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29087510 | 0.77 | SMPD1 (0.43) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL10706328 | 0.77 | SMPD1 (0.43) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL28207819 | 0.77 | MEN1 (0.45) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL21109970 | 0.77 | CYP4F2 (0.50) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL27212835 | 0.77 | CES2 (0.41) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL25078774 | 0.77 | CYP4F2 (0.50) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL31036743 | 0.77 | CES2 (0.41) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL19509962 | 0.77 | CES2 (0.46) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL18612496 | 0.77 | CES2 (0.46) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL19510111 | 0.77 | CYP4F2 (0.50) | MEN1MAPTKMT2AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114394-A | Polyamine derivatives as radioprotective agents | MERRELL PHARMACEUTICALS INC. (US) | 2000-09-05 | — | — | US | disclosed |