SCHEMBL8021452

SCHEMBL8021452

O=S(=O)(O)c1ccc2nc(S)[nH]c2c1.[NaH]

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.58
GAA P10253 1/20 0.45
HSD17B10 Q99714 1/20 0.45
SCD O00767 5/20 0.42
NPBWR1 P48145 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.39
IDO1 P14902 1/20 0.39
PARP1 P09874 1/20 0.38
CBFB Q13951 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MEN1 O00255 1/20 0.38
THRB P10828 1/20 0.38
APEX1 P27695 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4681427 0.98 HDAC6 (0.60) HDAC6GAAHSD17B10SCDNPBWR1
SCHEMBL1160169 0.98 HDAC6 (0.60) HDAC6GAAHSD17B10SCDNPBWR1
Water SCHEMBL28362651 0.97 HDAC6 (0.58) HDAC6GAAHSD17B10SCDNPBWR1
SCHEMBL2817420 0.87 HDAC6 (0.44) HDAC6GAAHSD17B10L3MBTL1PARP1
Water SCHEMBL28362573 0.86 HDAC6 (0.43) HDAC6GAAHSD17B10L3MBTL1PARP1
SCHEMBL1160168 0.85 HDAC6 (0.46) HDAC6GAAHSD17B10L3MBTL1PARP1
Water SCHEMBL28362650 0.84 HDAC6 (0.44) HDAC6GAAHSD17B10L3MBTL1PARP1
SCHEMBL2817421 0.82 NPBWR1 (0.42) HDAC6SCDNPBWR1IDO1CBFB
SCHEMBL3391201 0.82 CA12 (0.53) HDAC6SCDNPBWR1IDO1KDM4E
SCHEMBL8089242 0.82 NPBWR1 (0.60) SCDNPBWR1CBFB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0713131-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 2000-02-02 EP disclosed
EP-0629910-B1 A silver halide photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1998-09-09 EP disclosed
EP-0713131-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1996-05-22 EP disclosed
EP-0629910-A1 A silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1994-12-21 EP disclosed