Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8022488 | 0.99 | HTT (0.43) | HTTL3MBTL1SMN1; SMN2NPC1MAPT | |
| SCHEMBL6549825 | 0.98 | HTT (0.43) | HTTL3MBTL1SMN1; SMN2NPC1MAPT | |
| SCHEMBL6548648 | 0.88 | L3MBTL1 (0.55) | HTTL3MBTL1SMN1; SMN2MAPTHRH3 | |
| SCHEMBL6549311 | 0.88 | L3MBTL1 (0.50) | HTTL3MBTL1SMN1; SMN2NPC1MAPT | |
| SCHEMBL6549409 | 0.87 | GAA (0.56) | HTTL3MBTL1SMN1; SMN2MAPTHRH3 | |
| SCHEMBL8894549 | 0.87 | TP53 (0.47) | HTTL3MBTL1TP53TSHR | |
| SCHEMBL3969509 | 0.87 | HTT (0.42) | HTTL3MBTL1SMN1; SMN2NPC1MAPT | |
| SCHEMBL8022565 | 0.87 | HTT (0.52) | HTTL3MBTL1SMN1; SMN2NPC1MAPT | |
| SCHEMBL8897462 | 0.86 | TP53 (0.49) | HTTL3MBTL1TP53TSHR | |
| SCHEMBL6547877 | 0.86 | L3MBTL1 (0.51) | HTTL3MBTL1SMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975586-A2 | OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | Sumitomo Chemical Company, Limited (JP) | 2000-02-02 | — | — | EP | claimed |
| WO-1998045254-A2 | OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-10-15 | — | — | WO | claimed |