Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8022213 | 0.94 | L3MBTL1 (0.46) | L3MBTL1ATMELANEMAPTCYP1A2 | |
| SCHEMBL6220966 | 0.74 | ATM (0.51) | L3MBTL1ATMELANEMAPTCYP1A2 | |
| SCHEMBL20953994 | 0.71 | HDAC1 (0.37) | MAPTCYP1A2KMT2AMEN1ALDH1A1 | |
| SCHEMBL28703056 | 0.71 | ATM (0.50) | L3MBTL1ATMELANEMAPTCYP1A2 | |
| SCHEMBL28398100 | 0.70 | CHRM1 (0.33) | TDP1LMNAHSD17B10 | |
| SCHEMBL19105238 | 0.69 | TDP1 (0.53) | L3MBTL1ATMELANEMAPTCYP1A2 | |
| SCHEMBL28668235 | 0.69 | ELANE (0.50) | L3MBTL1ATMELANEMAPTCYP1A2 | |
| SCHEMBL7914370 | 0.69 | HDAC1 (0.54) | L3MBTL1ATMELANEMAPTCYP1A2 | |
| SCHEMBL27359972 | 0.69 | TDP1 (0.53) | L3MBTL1ATMALDH1A1KDM4ETDP1 | |
| SCHEMBL28008714 | 0.69 | ELANE (0.43) | L3MBTL1ATMELANEMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6072073-A | REACTING COMPOUND HAVING CARBONYL GROUP WITH ARYLATING OR VINYLATING COMPOUND IN PRESENCE OF BASE AND TRANSITION METAL CATALYST | YALE UNIVERSITY (US) | 2000-06-06 | — | — | US | disclosed |