SCHEMBL8022243

SCHEMBL8022243

COc1cc(/N=N/c2ccc(S(=O)(=O)O)cc2S(=O)(=O)O)c(C)cc1N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 6/20 0.53
SENP3 Q9H4L4 3/20 0.44
SENP2 Q9HC62 3/20 0.44
SENP1 Q9P0U3 3/20 0.44
SUMO2 P61956 2/20 0.44
SUMO1 P63165 2/20 0.44
SENP7 Q9BQF6 2/20 0.44
P2RX5 Q93086 2/20 0.44
P2RX4 Q99571 2/20 0.44
P2RX2 Q9UBL9 2/20 0.44
TP53 P04637 2/20 0.43
BRD4 O60885 1/20 0.43
CREBBP Q92793 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HTT P42858 1/20 0.42
ALDH1A1 P00352 3/20 0.42
HIF1A Q16665 1/20 0.42
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8022246 1.00 ENPP2 (0.53) ENPP2SENP3SENP2SENP1SUMO2
SCHEMBL19958196 0.99 ENPP2 (0.52) ENPP2SENP3SENP2SENP1SUMO2
SCHEMBL19235104 0.93 ENPP2 (0.57) ENPP2SENP3SENP2SENP1SUMO2
SCHEMBL20614139 0.91 ENPP2 (0.49) ENPP2SENP3SENP2SENP1SUMO2
SCHEMBL8021380 0.90 ENPP2 (0.53) ENPP2SENP3SENP2SENP1SUMO2
SCHEMBL8021383 0.90 ENPP2 (0.53) ENPP2SENP3SENP2SENP1SUMO2
SCHEMBL14923352 0.90 ENPP2 (0.56) ENPP2SENP3SENP2SENP1SUMO2
SCHEMBL10537455 0.88 ENPP2 (0.44) ENPP2SENP3SENP2SENP1SUMO2
SCHEMBL14923353 0.88 ENPP2 (0.52) ENPP2SENP3SENP2SENP1SUMO2
SCHEMBL9612332 0.87 ENPP2 (0.51) ENPP2SENP3SENP2SENP1SUMO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6060591-A FOR DYEING A MATERIAL CONTAINING HYDROXY OR CARBOXAMIDE GROUPS OR BOTH DY STAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND K.G. (DE) 2000-05-09 US disclosed
US-5834601-A DYEING CELLULOSE, WOOL, POLYAMIDE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-11-10 US disclosed
US-5731421-A COLORFASTNESS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-03-24 US disclosed
US-5591834-A AZO, PHTHALOCYANINE, AND DIOXAZINE DYES FOR COTTON AND POLYAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-01-07 US disclosed
US-5530104-A SUITABLE FOR DYEING AND PRINTING O CELLULOSE-CONTAINING FIBER MATERIAL; GOOD COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1996-06-25 US disclosed
US-5401277-A For cotton BAYER AKTIENGESELLSCHAFT (DE) 1995-03-28 US disclosed
US-5399674-A Dyestuffs containing pyrimidine-carboxylic acid amide radical having fiber-reactive group, processes for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1995-03-21 US disclosed
US-5391718-A Suitable for dyeing and printing of cellulose containing fibers; good colorfastness CIBA-GEIGY CORPORATION (US) 1995-02-21 US disclosed
US-5378817-A FOR DYEING COTTON BAYER AKTIENGESELLSCHAFT (DE) 1995-01-03 US disclosed
US-5342927-A Containing 2,4-difluoropyrimidine group; wet fastness BAYER AKTIENGESELLSCHAFT (DE) 1994-08-30 US disclosed
US-4801694-A Triazinyl reactive dyestuffs in which triazinyl group is further substituted with a beta-chloroethylsulfonyl- or vinylsulfonylbutyrylamino moiety CIBA-GEIGY CORPORATION (US) 1989-01-31 US disclosed
US-4786721-A DYEING OR PRINTING CELLULOSE FIBERS CIBA-GEIGY CORPORATION (US) 1988-11-22 US disclosed
US-4766206-A Reactive dyestuffs comprising a vinylsulfonylalkylaminocarbonyl moiety CIBA-GEIGY CORPORATION (US) 1988-08-23 US disclosed
US-4746732-A COTTON AND WOOL CIBA-GEIGY CORPORATION (US) 1988-05-24 US disclosed
US-4713082-A Process for dyeing or printing textile fibre materials with reactive dye containing vinyl sulfonyl-type group and chloro-triazinyl amino group CIBA-GEIGY CORPORATION (US) 1987-12-15 US disclosed
US-4709018-A COLORFAST CIBA-GEIGY CORPORATION (US) 1987-11-24 US disclosed
US-4631065-A Reactive dyes, process for their preparation and use thereof CIBA-GEIGY CORPORATION (US) 1986-12-23 US disclosed
US-4568350-A Cold pad-batch process for dyeing silk or silk-containing fiber blends with reactive dyes CIBA-GEIGY CORPORATION (US) 1986-02-04 US disclosed
US-4560388-A WITH SULFO GROUP CONTAINING FIBER REACTIVE DYE CIBA-GEIGY CORPORATION (US) 1985-12-24 US disclosed
US-4523925-A Process for dyeing or printing cellulose textile fiber materials with reactive dyes containing fluoro-triazine CIBA-GEIGY CORPORATION (US) 1985-06-18 US disclosed