Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | ACR | P10323 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026283 | 0.87 | NPC1 (0.48) | NPC1RAB9AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8026280 | 0.87 | NPC1 (0.48) | NPC1RAB9AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL26418832 | 0.82 | MEN1 (0.47) | NPC1RAB9AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8026084 | 0.81 | PPARG (0.48) | NPC1RAB9AHIF1ASMN1; SMN2HPGD | |
| SCHEMBL8026096 | 0.79 | NOTUM (0.37) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL21647869 | 0.79 | NOTUM (0.37) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8026099 | 0.79 | NOTUM (0.37) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL21675874 | 0.79 | NOTUM (0.37) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL26418271 | 0.79 | NOTUM (0.37) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7695019 | 0.78 | LMNA (0.54) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975587-A1 | OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998043949-A1 | OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-10-08 | — | — | WO | disclosed |