Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | TYR | P14679 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2863685 | 0.89 | LTA4H (0.46) | LTA4HHPGDMAPK1NPSR1HTT | |
| SCHEMBL980196 | 0.88 | LTA4H (0.42) | LTA4HTYRHPGDMAPK1NPSR1 | |
| SCHEMBL28036404 | 0.88 | TYR (0.49) | LTA4HTYRHPGDMAPK1NPSR1 | |
| SCHEMBL980418 | 0.86 | TYR (0.47) | LTA4HTYRHTTMEN1TP53 | |
| SCHEMBL2352866 | 0.85 | TYR (0.45) | LTA4HTYRHPGDMAPK1NPSR1 | |
| SCHEMBL2862335 | 0.85 | LTA4H (0.46) | LTA4HTYRALOX5 | |
| SCHEMBL984506 | 0.85 | TYR (0.49) | LTA4HTYRHTTMEN1TP53 | |
| SCHEMBL984779 | 0.85 | TYR (0.49) | LTA4HTYRHTTMEN1TP53 | |
| SCHEMBL984396 | 0.85 | TYR (0.49) | LTA4HTYRHTTMEN1TP53 | |
| SCHEMBL980410 | 0.85 | TYR (0.49) | LTA4HTYRHTTMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143905-A | REACTING 1,7-DIBROMOPERYLENE-3,4,9,10-TETRACARBOXYLIC DIANHYDRIDE OR TETRACARBOXYLIC ACID IN PRESENCE OF APROTIC SOLVENT WITH A PRIMARY AMINE TO FORM DIIMIDE, REACTING DIIMIDE WITH AROMATIC ALOCHOL OR THIOL, AND HYDROLYZING | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-07 | — | — | US | disclosed |