Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357072 | 0.84 | CYP4F2 (0.42) | MAPTMAPK1TAAR1CYP4F2CYP4A11 | |
| SCHEMBL119714 | 0.84 | CYP4F2 (0.42) | MAPTMAPK1TAAR1CYP4F2CYP4A11 | |
| SCHEMBL8098955 | 0.82 | CYP17A1 (0.56) | CYP17A1CYP11B1CYP11B2KIF11CYP3A4 | |
| SCHEMBL29993075 | 0.81 | AHR (0.55) | FFAR1AHRMAPK1CYP3A4KMO | |
| SCHEMBL8092321 | 0.79 | AHR (0.44) | FFAR1CYP11B1CYP11B2AHRMAPK1 | |
| SCHEMBL30466107 | 0.78 | RARB (0.47) | FFAR1CYP17A1CYP11B1CYP11B2MAPT | |
| SCHEMBL8857916 | 0.78 | RARB (0.47) | FFAR1CYP17A1CYP11B1CYP11B2MAPT | |
| SCHEMBL31067094 | 0.77 | AHR (0.46) | FFAR1CYP11B1CYP11B2AHRKMO | |
| SCHEMBL7770631 | 0.77 | TAAR1 (0.42) | FFAR1CYP17A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL4425776 | 0.77 | MAPT (0.44) | FFAR1CYP17A1CYP11B1CYP11B2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670322-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2000-01-19 | — | — | EP | disclosed |
| US-5582764-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0670322-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-09-06 | — | — | EP | disclosed |