SCHEMBL8022686

SCHEMBL8022686

C=CCn1c(Cl)c(Cl)[n+](C)c1Cl

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.37
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8021952 0.98 CYP3A4 (0.35) CYP3A4CYP1A2CYP2D6
SCHEMBL8027716 0.82 CYP3A4 (0.35) CYP3A4CYP1A2CYP2D6KDM4EMEN1
Hydrochloric Acid SCHEMBL8023885 0.81 CYP3A4 (0.34) CYP3A4CYP1A2CYP2D6KDM4EMEN1
SCHEMBL6901229 0.61 HDAC8 (0.33)
SCHEMBL3313929 0.61 CYP3A4 (0.38) CYP3A4KDM4EMEN1HPGDKMT2A
SCHEMBL20861812 0.60 CYP3A4 (0.46) CYP3A4KDM4EMEN1HPGDKMT2A
Hydrochloric Acid SCHEMBL8003549 0.60 HDAC8 (0.32)
SCHEMBL1426816 0.59 KMT2A (0.46) CYP3A4CYP1A2CYP2D6KDM4EMEN1
Hydrochloric Acid SCHEMBL4088358 0.58 KMT2A (0.45) CYP3A4CYP1A2CYP2D6KDM4EMEN1
SCHEMBL10282695 0.55 CYP3A4 (0.52) CYP3A4CYP1A2CYP2D6KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000037400-A1 HALOGENATION IN IONIC LIQUIDS INEOS CHLOR LIMITED (GB) 2000-06-29 WO claimed