Valine

Valine

SCHEMBL8022867

CC(C)[C@H](N)C(=O)O.CCCCO

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.62
ALDH1A1 P00352 2/20 0.46
DPP4 P27487 1/20 0.41
DPP8 Q6V1X1 1/20 0.41
DPP9 Q86TI2 1/20 0.41
DPP7 Q9UHL4 1/20 0.41
SLC1A2 P43004 3/20 0.40
SLC1A1 P43005 3/20 0.40
SLC1A3 P43003 2/20 0.40
GRIK1 P39086 3/20 0.39
GRIK2 Q13002 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CHRM1 P11229 1/20 0.38
AKR1A1 P14550 1/20 0.38
CHRM3 P20309 1/20 0.38
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
ADRA1A P35348 1/20 0.38
HRH1 P35367 1/20 0.38
DRD3 P35462 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Octanol SCHEMBL2214937 0.92 SLC7A5 (0.58) SLC7A5ALDH1A1DPP4DPP8DPP9
Valine SCHEMBL4045692 0.89 SLC7A5 (0.71) SLC7A5DPP4DPP8DPP9DPP7
Valine SCHEMBL30099875 0.89 SLC7A5 (0.71) SLC7A5DPP4DPP8DPP9DPP7
Valine SCHEMBL9667518 0.89 SLC7A5 (0.71) SLC7A5SLC1A2SLC1A1SLC1A3
Valine SCHEMBL1685902 0.89 SLC7A5 (0.71) SLC7A5SLC1A2SLC1A1SLC1A3GPR84
Dodecane SCHEMBL28109673 0.87 SLC7A5 (0.68) SLC7A5ALDH1A1SLC1A2SLC1A1GRIK1
Valine SCHEMBL11005807 0.87 SLC7A5 (0.68) SLC7A5ALDH1A1SLC1A2SLC1A1GRIK1
Threonine SCHEMBL10440654 0.86 ALDH1A1 (0.44) SLC7A5ALDH1A1SLC1A2SLC1A1SLC1A3
Valine SCHEMBL28555130 0.86 SLC7A5 (0.60) SLC7A5ALDH1A1DPP4DPP8DPP9
Cetostearyl Alcohol SCHEMBL28667843 0.84 SLC7A5 (0.48) SLC7A5ALDH1A1SLC1A2SLC1A1GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017117212-A1 (R)-12-HYDROXYSTEARIC ACID HYDRAZIDES AS GELATORS AND SELF-STANDING GELS THEREOF GEORGETOWN UNIVERSITY (US) 2017-07-06 WO disclosed
EP-0983986-A1 Process for separating 1,3-butadiene and water from mixtures containing them and 1-n-butoxy-2-butene, 3-n-butoxy-1-butene, n-butanol and di-n-butyl ether BASF AKTIENGESELLSCHAFT (DE) 2000-03-08 EP disclosed