Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.97 |
| ▸ | HTT | P42858 | 2/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.97 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.97 |
| ▸ | ACHE | P22303 | 12/20 | 0.85 |
| ▸ | BCHE | P06276 | 9/20 | 0.85 |
| ▸ | BACE1 | P56817 | 1/20 | 0.85 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366446 | 0.97 | KDM4E (0.92) | MEN1HTTKMT2AKDM4EACHE | |
| SCHEMBL15155625 | 0.87 | KDM4E (0.74) | MEN1HTTKMT2AKDM4EACHE | |
| SCHEMBL12043396 | 0.86 | BCHE (0.92) | MEN1HTTKMT2AKDM4EACHE | |
| SCHEMBL29062227 | 0.85 | KDM4E (0.72) | MEN1HTTKMT2AKDM4EACHE | |
| SCHEMBL3361969 | 0.85 | KDM4E (0.72) | MEN1HTTKMT2AKDM4EACHE | |
| SCHEMBL13480595 | 0.84 | BCHE (0.76) | ACHEBCHEBACE1 | |
| SCHEMBL12043399 | 0.83 | BCHE (0.97) | ACHEBCHEBACE1 | |
| SCHEMBL16223230 | 0.83 | ACHE (0.72) | MEN1HTTKMT2AKDM4EACHE | |
| SCHEMBL12043397 | 0.82 | BCHE (0.95) | ACHEBCHEBACE1 | |
| SCHEMBL12043400 | 0.82 | BCHE (0.95) | ACHEBCHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130228-A | Polycyclic compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2000-10-10 | — | — | US | disclosed |