Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11789880 | 0.82 | ALDH1A1 (0.47) | ALDH1A1ALOX15PTPN1LMNAHSD17B10 | |
| SCHEMBL11789874 | 0.82 | ALDH1A1 (0.47) | ALDH1A1ALOX15PTPN1LMNAHSD17B10 | |
| SCHEMBL8015613 | 0.78 | ALDH1A1 (0.44) | ALDH1A1ALOX15PTPN1LMNAHSD17B10 | |
| SCHEMBL8015610 | 0.78 | ALDH1A1 (0.44) | ALDH1A1ALOX15PTPN1LMNAHSD17B10 | |
| SCHEMBL11402672 | 0.78 | ALDH1A1 (0.44) | ALDH1A1ALOX15PTPN1LMNAHSD17B10 | |
| SCHEMBL10782837 | 0.78 | ALDH1A1 (0.44) | ALDH1A1ALOX15PTPN1LMNAHSD17B10 | |
| SCHEMBL10782842 | 0.78 | ALDH1A1 (0.44) | ALDH1A1ALOX15PTPN1LMNAHSD17B10 | |
| SCHEMBL8008448 | 0.77 | ALDH1A1 (0.44) | ALDH1A1ALOX15PTPN1LMNAHSD17B10 | |
| SCHEMBL8008451 | 0.77 | ALDH1A1 (0.44) | ALDH1A1ALOX15PTPN1LMNAHSD17B10 | |
| SCHEMBL1871028 | 0.75 | ALDH1A1 (0.65) | ALDH1A1ALOX15PTPN1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6018075-A | BY REACTING GAMMA-BROMOTIGLIC ALDEHYDE OR GAMMA-CHLOROTIGLIC ALDEHYDE WITH SODIUM OR POTASSIUM ACETATE IN THE PRESENCE OF A PHASE TRANSFER CATALYST AND ORGANIC SOLVENT | ROCHE VITAMINS INC. (US) | 2000-01-25 | — | — | US | disclosed |
| US-5990360-A | DEETHERIFICATION IN PRESENCE OF AN ALUMINIUM SILICATE CATALYST | ROCHE VITAMINS INC. (US) | 1999-11-23 | — | — | US | disclosed |
| US-5786518-A | HALOHYDROXYLATION OF ALKOXY-2-METHYL-1,3-BUTADIENE WITH ALKANOL AND HALOGEN THEN HYDROLYSIS | ROCHE VITAMINS INC. (US) | 1998-07-28 | — | — | US | disclosed |