SCHEMBL8023707

SCHEMBL8023707

OCCc1cc2ccccc2cc1Cl

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.38
CYP2A6 P11509 2/20 0.37
KMT2A Q03164 1/20 0.36
GRIN1 Q05586 1/20 0.35
GRIN2B Q13224 1/20 0.35
RHEB Q15382 1/20 0.35
PKM P14618 1/20 0.34
TRPV1 Q8NER1 1/20 0.34
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
MRGPRX4 Q96LA9 1/20 0.33
CYP1A2 P05177 2/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27997437 0.84 TDP1 (0.46) TDP1CYP2A6PKMCYP4F2CYP4A11
SCHEMBL20562979 0.83 CBFB (0.43) CYP2A6KMT2AGRIN1GRIN2BCYP1A2
SCHEMBL2313052 0.80 TDP1 (0.42) TDP1CYP2A6PKMCYP4F2CYP4A11
SCHEMBL20563261 0.79 TAAR1 (0.57) TAAR1
SCHEMBL13395654 0.76 KMT2A (0.53) TDP1CYP2A6KMT2AGRIN1GRIN2B
SCHEMBL29700257 0.76 KMT2A (0.53) TDP1CYP2A6KMT2AGRIN1GRIN2B
SCHEMBL8035450 0.75 TDP1 (0.38) TDP1CYP2A6CYP4F2CYP4A11TAAR1
SCHEMBL15310451 0.75 IDO1 (0.42) TDP1CYP4F2CYP4A11CYP1A2
SCHEMBL15345788 0.74 PNMT (0.54) CYP2A6KMT2AGRIN1GRIN2BTAAR1
SCHEMBL2316615 0.74 TDP1 (0.41) TDP1CYP4F2CYP4A11CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6022822-A Organotin compound and catalyst for transesterification comprising the same RYOJI NOYORI (JP) 2000-02-08 US disclosed