Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.58 |
| ▸ | REN | P00797 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PEPD | P12955 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947053 | 1.00 | ACE (0.58) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL9422545 | 0.87 | ACE (0.57) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL8444919 | 0.87 | ACE (0.43) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL11370643 | 0.86 | ACE (0.56) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL9472773 | 0.86 | ACE (0.56) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL11559055 | 0.85 | ACE (0.80) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL7377582 | 0.85 | PEPD (0.49) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL11301917 | 0.84 | ACE (0.73) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL6950273 | 0.84 | ACE (0.58) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL11372050 | 0.83 | ACE (0.49) | ACERENLMNAHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000212199-A | PRODUCTION OF 1-[(S)-3-ACETYLTHIO-2-METHYLPROPANOYL-L- PROLYL-L-PHENYLALANINE AND INTERMEDIATE THEREOF | OHARA YAKUHIN KOGYO KK | 2000-08-02 | — | — | JP | disclosed |
| JP-2000143693-A | PRODUCTION OF 1-[(S)-3-ACETYLTHIO-2-METHYLPROPANOYL]-L- PROLYL-L-PHENYLALANINE AND INTERMEDIATE | OHARA YAKUHIN KOGYO KK | 2000-05-26 | — | — | JP | disclosed |
| US-5387697-A | Process for the preparation of 1-[3-acetylthio-2(s)-methylpropanoyl]-l-proline | MERCK & CO., INC. (US) | 1995-02-07 | — | — | US | disclosed |