Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8016924 | 0.89 | SRD5A1 (0.47) | SRD5A1SRD5A2 | |
| SCHEMBL8006816 | 0.85 | SRD5A1 (0.70) | SRD5A1SRD5A2 | |
| SCHEMBL8020671 | 0.82 | SRD5A1 (0.47) | SRD5A1SRD5A2 | |
| SCHEMBL8019151 | 0.82 | SRD5A1 (0.46) | SRD5A1SRD5A2 | |
| SCHEMBL8017223 | 0.75 | SRD5A1 (0.74) | SRD5A1SRD5A2 | |
| SCHEMBL8006689 | 0.75 | SRD5A2 (0.47) | SRD5A1SRD5A2 | |
| SCHEMBL8023739 | 0.74 | SRD5A1 (0.44) | SRD5A1SRD5A2 | |
| SCHEMBL8016927 | 0.73 | SRD5A1 (0.64) | SRD5A1SRD5A2 | |
| SCHEMBL8017214 | 0.71 | SRD5A1 (0.53) | SRD5A1SRD5A2 | |
| SCHEMBL8006808 | 0.71 | SRD5A1 (0.62) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664812-B1 | 17-BETA-ARYL ESTER CARBOXYLATES OF 4-AZA-5-ALPHA-ANDROSTANE-3-ONES | MERCK & CO INC (US) | 2000-01-05 | — | — | EP | disclosed |
| US-5278159-A | Steroid enzyme inhibitor | MERCK & CO., INC. (US) | 1994-01-11 | — | — | US | disclosed |