SCHEMBL8023741

SCHEMBL8023741

CCCCCCCCCC/C=C/N1CCCCC1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.47
TRPV1 Q8NER1 1/20 0.47
TSHR P16473 1/20 0.41
GMNN O75496 1/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX15 P16050 1/20 0.41
APEX1 P27695 1/20 0.41
CYP2C19 P33261 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27598798 1.00 FAAH (0.47) FAAHTRPV1TSHRGMNNUSP2
SCHEMBL9325525 1.00 FAAH (0.47) FAAHTRPV1TSHRGMNNUSP2
SCHEMBL9328599 1.00 FAAH (0.47) FAAHTRPV1TSHRGMNNUSP2
SCHEMBL8023742 1.00 FAAH (0.47) FAAHTRPV1TSHRGMNNUSP2
SCHEMBL9225054 1.00 FAAH (0.47) FAAHTRPV1TSHRGMNNUSP2
SCHEMBL9325532 1.00 FAAH (0.47) FAAHTRPV1TSHRGMNNUSP2
SCHEMBL9225064 1.00 FAAH (0.47) FAAHTRPV1TSHRGMNNUSP2
SCHEMBL9325631 1.00 FAAH (0.47) FAAHTRPV1TSHRGMNNUSP2
SCHEMBL9328601 1.00 FAAH (0.47) FAAHTRPV1TSHRGMNNUSP2
SCHEMBL9325629 1.00 FAAH (0.47) FAAHTRPV1TSHRGMNNUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6146547-A USEFUL AS COMPONENT OF FERROELECTRIC LIQUID CRYSTAL FORMULATIONS CHISSO CORPORATION (JP) 2000-11-14 US disclosed
EP-0278665-B1 2-Substituted-alkyl ether and liquid crystal composition CHISSO CORP (JP) 1994-09-21 EP disclosed
EP-0361157-B1 Phenyl pyridines HOFFMANN LA ROCHE (CH) 1994-03-02 EP disclosed
US-5284956-A Liquid crystalline mixtures containing 2-(2-fluorophenyl) pyridines HOFFMANN-LA ROCHE INC. (US) 1994-02-08 US disclosed
US-5120468-A Optical active mixture exhibiting ferroelectricity CHISSO CORPORATION (JP) 1992-06-09 US disclosed
EP-0361157-A1 Phenyl pyridines F. HOFFMANN-LA ROCHE AG (CH) 1990-04-04 EP disclosed
EP-0278665-A2 2-Substituted-alkyl ether and liquid crystal composition Chisso Corporation (JP) 1988-08-17 EP disclosed
US-4752413-A LIQUID CRYSTALS CHISSO CORPORATION (JP) 1988-06-21 US disclosed
EP-0247804-A2 2-(Alkyloxycarbonyloxyphenyl)-5-alkylpyridine and composition containing same Chisso Corporation (JP) 1987-12-02 EP disclosed