Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.43 |
| ▸ | FNTB | P49356 | 4/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928051 | 0.86 | RNPEP (0.54) | LMNARNPEPFOLH1CA2CA1 | |
| SCHEMBL5869722 | 0.83 | FOLH1 (0.58) | LMNARNPEPFOLH1ALDH1A1NPSR1 | |
| SCHEMBL8248682 | 0.83 | FOLH1 (0.58) | LMNARNPEPFOLH1ALDH1A1NPSR1 | |
| SCHEMBL5869735 | 0.79 | RNPEP (0.47) | LMNARNPEPFOLH1CA2CA1 | |
| SCHEMBL8255152 | 0.79 | RNPEP (0.47) | LMNARNPEPFOLH1CA2CA1 | |
| SCHEMBL5870088 | 0.79 | RNPEP (0.47) | LMNARNPEPFOLH1CA2CA1 | |
| SCHEMBL8255575 | 0.79 | RNPEP (0.47) | LMNARNPEPFOLH1CA2CA1 | |
| Racemethionine SCHEMBL28667932 | 0.78 | FNTA (0.47) | FNTAFNTBPGGT1BLMNARNPEP | |
| SCHEMBL9911535 | 0.77 | LMNA (0.51) | LMNARNPEPFOLH1CA2CA1 | |
| SCHEMBL15592739 | 0.77 | LMNA (0.51) | LMNARNPEPFOLH1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972074-A1 | A METHOD FOR IDENTIFYING THE SITE OF ACTION OF XENOBIOTIC CHEMICALS | E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998038336-A1 | A METHOD FOR IDENTIFYING THE SITE OF ACTION OF XENOBIOTIC CHEMICALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-09-03 | — | — | WO | disclosed |