SCHEMBL80238

SCHEMBL80238

CC1(C)c2ccccc2-c2cc(-c3cccc(-c4ccc5c(n4)-c4ccccc4C5(C)C)c3)ccc21

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 16/20 0.36
ENPP3 O14638 1/20 0.33
RARA P10276 2/20 0.32
RARB P10826 2/20 0.32
RARG P13631 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL81461 0.95 PDK2 (0.39) PDK2ENPP3
SCHEMBL81159 0.95 PDK2 (0.39) PDK2ENPP3
SCHEMBL81053 0.95 PDK2 (0.39) PDK2ENPP3
SCHEMBL81689 0.94 RARA (0.33) PDK2ENPP3RARARARBRARG
SCHEMBL81490 0.94 PDK2 (0.33) PDK2ENPP3RARARARBRARG
SCHEMBL81002 0.94 PDK2 (0.33) PDK2RARARARBRARG
SCHEMBL80242 0.94 PDK2 (0.33) PDK2ENPP3RARARARBRARG
SCHEMBL81931 0.93 PDK2 (0.35) PDK2
SCHEMBL10036759 0.93 KMT2A (0.34) PDK2ENPP3RARARARB
SCHEMBL80301 0.93 KMT2A (0.34) PDK2RARARARBRARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129899-B1 Azafluorene derivative and organic light-emitting device using the derivative CANON KABUSHIKI KAISHA (JP) 2012-03-06 US disclosed
US-8129899-B1 Azafluorene derivative and organic light-emitting device using the derivative CANON KABUSHIKI KAISHA (JP) 2012-03-06 US disclosed