Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.55 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8567005 | 0.99 | GBA1 (0.54) | GBA1SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL4432223 | 0.92 | ALDH1A1 (0.56) | GBA1SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL3449699 | 0.90 | ALDH1A1 (0.55) | GBA1SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL3730989 | 0.90 | ALDH1A1 (0.55) | GBA1SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL9497964 | 0.90 | ALDH1A1 (0.55) | GBA1SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4438846 | 0.89 | ALDH1A1 (0.54) | GBA1SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL10825521 | 0.87 | ALDH1A1 (0.56) | GBA1SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL1768517 | 0.87 | CA1 (0.63) | SLC1A3SLC1A2SLC1A1ALDH1A1MEN1 | |
| SCHEMBL2234191 | 0.87 | CA1 (0.63) | SLC1A3SLC1A2SLC1A1ALDH1A1MEN1 | |
| SCHEMBL2235887 | 0.86 | ALDH1A1 (0.54) | GBA1SLC1A3SLC1A2SLC1A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973733-A1 | BIS-SULFONOMIDES HYDROXAMIC ACIDS AS MMP INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| US-5859061-A | MATRIX METALLOPROTEINASE INHIBITORS; TREATING DISEASES INVOLVING CONNECTIVE TISSUE DEGRADATION | PHARMACIA & UPJOHN COMPANY (US) | 1999-01-12 | — | — | US | disclosed |
| WO-1998031664-A1 | BIS-SULFONOMIDES HYDROXAMIC ACIDS AS MMP INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1998-07-23 | — | — | WO | disclosed |