SCHEMBL8023913

SCHEMBL8023913

O=C(O)c1ccc(CCl)cc1.[KH]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.61
CA2 P00918 4/20 0.61
ALDH1A1 P00352 4/20 0.58
TSHR P16473 3/20 0.57
TP53 P04637 1/20 0.57
ALOX15 P16050 1/20 0.52
KMT2A Q03164 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 1/20 0.52
USP2 O75604 1/20 0.52
POLB P06746 1/20 0.52
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
THRB P10828 1/20 0.52
NR4A1 P22736 1/20 0.52
APEX1 P27695 1/20 0.52
APOBEC3A P31941 1/20 0.52
RECQL P46063 1/20 0.52
HIF1A Q16665 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27700157 0.98 CA1 (0.64) CA1CA2ALDH1A1TSHRTP53
SCHEMBL40281 0.98 CA1 (0.64) CA1CA2ALDH1A1TSHRTP53
Hydrochloric Acid SCHEMBL1597978 0.95 CA1 (0.61) CA1CA2ALDH1A1TSHRTP53
SCHEMBL8029236 0.95 CA1 (0.61) CA1CA2ALDH1A1TSHRTP53
Ammonia Solution, Strong SCHEMBL29216630 0.95 CA1 (0.61) CA1CA2ALDH1A1TSHRTP53
Bromide SCHEMBL1596774 0.95 CA1 (0.61) CA1CA2ALDH1A1TSHRTP53
SCHEMBL28111598 0.93 CA1 (0.59) CA1CA2ALDH1A1TSHRTP53
SCHEMBL3618354 0.87 CA1 (0.53) CA1CA2ALDH1A1TSHRTP53
SCHEMBL9828068 0.82 CA1 (0.53) CA1CA2ALDH1A1TSHRTP53
Benzamide SCHEMBL5499602 0.82 PLA2G10 (0.59) CA1CA2ALDH1A1TSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1137923-C Silicon-containing block-copolymer ������ҩ��ҵ��ʽ���� 2004-02-11 CN disclosed
EP-0779318-B1 Silicon-containing block copolymer WAKO PURE CHEMICAL INDUSTIES L (JP) 2000-02-16 EP disclosed
US-5760136-A FORMING AN ADDITION-CONDENSATION COPOLYMER BY POLYMERIZING AN AZO-CONTAINING POLYSILOXANE AND AN UNSATURATED MONOMER; CATIONIC AND NONIONIC POLYMERS; POLYAMPHOLYTES; COATINGS; ADHESIVES; PAINTS; HAIR COSMETICS WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1998-06-02 US disclosed
CN-1157834-A Silicon-containing block-copolymer WAKO PURE CHEM IND LTD (JP) 1997-08-27 CN disclosed
EP-0779318-A1 Silicon-containing block copolymer Wako Pure Chemical Industries, Ltd. (JP) 1997-06-18 EP disclosed