Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186305 | 0.87 | CA2 (0.61) | PLA2G10PLA2G2ATSHRPOLBCYP3A4 | |
| Phenol SCHEMBL7153494 | 0.86 | PLA2G10 (0.59) | PLA2G10PLA2G2ATSHRPOLBCYP3A4 | |
| Terephthalamide SCHEMBL28689227 | 0.84 | TSHR (0.80) | PLA2G10PLA2G2ATSHRPOLBCYP3A4 | |
| Terephthalic Acid SCHEMBL28758019 | 0.84 | TSHR (0.80) | PLA2G10PLA2G2ATSHRPOLBCYP3A4 | |
| SCHEMBL27700157 | 0.84 | CA1 (0.64) | TSHRPOLBMAPTRECQLTDP1 | |
| SCHEMBL40281 | 0.84 | CA1 (0.64) | TSHRPOLBMAPTRECQLTDP1 | |
| SCHEMBL8023913 | 0.82 | CA1 (0.61) | TSHRPOLBMAPTRECQLTDP1 | |
| Hydrochloric Acid SCHEMBL1597978 | 0.82 | CA1 (0.61) | TSHRPOLBMAPTRECQLTDP1 | |
| Bromide SCHEMBL1596774 | 0.82 | CA1 (0.61) | TSHRPOLBMAPTRECQLTDP1 | |
| Ammonia Solution, Strong SCHEMBL29216630 | 0.82 | CA1 (0.61) | TSHRPOLBMAPTRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753750-A1 | THIOPHENE HETEROARYL AMINES | Sugen, Inc. (US) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005113548-A1 | THIOPHENE HETEROARYL AMINES | SUGEN, INC. (US) | 2005-12-01 | — | — | WO | disclosed |