SCHEMBL8023918

SCHEMBL8023918

CCCCCCCCCCCCCCc1nc(N)n[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
MAPT P10636 2/20 0.49
HPGD P15428 2/20 0.46
PKM P14618 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
NPC1 O15118 1/20 0.45
TP53 P04637 1/20 0.45
TSHR P16473 1/20 0.45
RAB9A P51151 1/20 0.45
LMNA P02545 1/20 0.41
PI4KA P42356 1/20 0.41
PI4K2B Q8TCG2 1/20 0.41
PI4K2A Q9BTU6 1/20 0.41
PI4KB Q9UBF8 1/20 0.41
GPR84 Q9NQS5 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8040018 1.00 ALDH1A1 (0.61) ALDH1A1MAPTHPGDPKMSMN1; SMN2
SCHEMBL534850 1.00 ALDH1A1 (0.61) ALDH1A1MAPTHPGDPKMSMN1; SMN2
SCHEMBL535003 1.00 ALDH1A1 (0.61) ALDH1A1MAPTHPGDPKMSMN1; SMN2
SCHEMBL534934 1.00 ALDH1A1 (0.61) ALDH1A1MAPTHPGDPKMSMN1; SMN2
SCHEMBL534987 1.00 ALDH1A1 (0.61) ALDH1A1MAPTHPGDPKMSMN1; SMN2
SCHEMBL8037782 1.00 ALDH1A1 (0.61) ALDH1A1MAPTHPGDPKMSMN1; SMN2
SCHEMBL535701 1.00 ALDH1A1 (0.61) ALDH1A1MAPTHPGDPKMSMN1; SMN2
SCHEMBL534856 1.00 ALDH1A1 (0.61) ALDH1A1MAPTHPGDPKMSMN1; SMN2
SCHEMBL535434 1.00 ALDH1A1 (0.61) ALDH1A1MAPTHPGDPKMSMN1; SMN2
Hydrochloric Acid SCHEMBL8040169 0.98 ALDH1A1 (0.59) ALDH1A1MAPTHPGDPKMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000077139-A1 MACHINE DISHWASHING DETERGENTS CONTAINING SPECIAL PHOSPHATES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2000-12-21 WO disclosed