Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17086663 | 0.85 | OPRM1 (0.50) | OPRM1OPRL1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL17086668 | 0.85 | OPRM1 (0.50) | OPRM1OPRL1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL17086655 | 0.81 | OPRM1 (0.47) | OPRM1OPRL1OPRD1OPRK1CHRM2 | |
| SCHEMBL19494132 | 0.81 | OPRM1 (0.47) | OPRM1OPRL1OPRD1OPRK1CHRM2 | |
| SCHEMBL17086666 | 0.81 | OPRM1 (0.47) | OPRM1OPRL1OPRD1OPRK1CHRM2 | |
| SCHEMBL17086664 | 0.81 | OPRM1 (0.47) | OPRM1OPRL1OPRD1OPRK1CHRM2 | |
| SCHEMBL17086651 | 0.81 | OPRM1 (0.47) | OPRM1OPRL1OPRD1OPRK1CHRM2 | |
| SCHEMBL8124662 | 0.79 | OPRM1 (0.46) | OPRM1OPRL1OPRD1OPRK1CHRM2 | |
| SCHEMBL9717862 | 0.79 | OPRM1 (0.46) | OPRM1OPRL1OPRD1OPRK1CHRM2 | |
| SCHEMBL7290614 | 0.76 | USP2 (0.45) | CYP2C9MEN1KMT2AOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780369-B1 | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol derivatives as pharmaceutical agents | GRUENENTHAL GMBH (DE) | 2000-01-19 | — | — | EP | disclosed |
| US-5801201-A | 1-phenyl-2-dimenthylaminomethyl-cyclohexan-1-ol compounds as pharmaceutical active ingredients | GRUENENTHAL GMBH (DE) | 1998-09-01 | — | — | US | disclosed |
| EP-0780369-A1 | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol derivatives as pharmaceutical agents | Grünenthal GmbH (DE) | 1997-06-25 | — | — | EP | disclosed |