SCHEMBL8023966

SCHEMBL8023966

O=C(O)c1cc(Cl)cc(Cl)c1.[KH]

nearest known ligand 0.94

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 3/20 0.94
HCAR1 Q9BXC0 1/20 0.70
RXRA P19793 2/20 0.58
RXRB P28702 2/20 0.58
TTR P02766 1/20 0.54
HCAR2 Q8TDS4 1/20 0.54
TSHR P16473 5/20 0.52
ALOX15 P16050 2/20 0.52
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48
CA14 Q9ULX7 2/20 0.48
SRD5A2 P31213 1/20 0.46
TP53 P04637 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
CA3 P07451 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28214359 0.97 TPMT (1.00) TPMTHCAR1RXRARXRBTTR
SCHEMBL23699 0.97 TPMT (1.00) TPMTHCAR1RXRARXRBTTR
Bromide SCHEMBL27041421 0.94 TPMT (0.94) TPMTHCAR1RXRARXRBTTR
Iodide SCHEMBL27041428 0.94 TPMT (0.94) TPMTHCAR1RXRARXRBTTR
Hydrochloric Acid SCHEMBL10387707 0.94 TPMT (0.94) TPMTHCAR1RXRARXRBTTR
SCHEMBL69625 0.92 TPMT (0.89) TPMTHCAR1RXRARXRBTTR
Hydrochloric Acid SCHEMBL11742420 0.89 TPMT (0.84) TPMTHCAR1RXRARXRBTTR
Hydrochloric Acid SCHEMBL3358926 0.89 TPMT (0.84) TPMTHCAR1RXRARXRBTTR
SCHEMBL28267562 0.87 TPMT (0.81) TPMTHCAR1RXRARXRBTTR
Terephthalic Acid SCHEMBL11195049 0.84 TPMT (0.76) TPMTHCAR1RXRARXRBTTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4077287-B1 EFFICIENT PROCESS FOR MAKING 6-CARBOXY BENZOXAZOLE DERIVATIVES PFIZER IRELAND PHARMACEUTICALS UNLIMITED COMPANY (IE) 2025-11-19 EP disclosed
US-20230090609-A1 Efficient Process For Making 6-Carboxy Benzoxazole Derivatives PFIZER IRELAND PHARMACEUTICALS (US) 2023-03-23 US disclosed
EP-4077287-A1 EFFICIENT PROCESS FOR MAKING 6-CARBOXY BENZOXAZOLE DERIVATIVES Pfizer Ireland Pharmaceuticals (IE) 2022-10-26 EP disclosed
CN-115135639-A Efficient process for preparing 6-carboxybenzoxazole derivatives 辉瑞爱尔兰制药公司 2022-09-30 CN disclosed
WO-2021124158-A1 EFFICIENT PROCESS FOR MAKING 6-CARBOXY BENZOXAZOLE DERIVATIVES PFIZER IRELAND PHARMACEUTICALS (IE) 2021-06-24 WO disclosed
EP-0669844-B1 METHOD FOR PREPARING VISCOELASTIC SURFACTANT BASED FOAM FLUIDS DOWELL SCHLUMBERGER INC (US) 2000-01-05 EP disclosed
EP-0669844-A4 VISCOELASTIC SURFACTANT BASED FOAM FLUIDS. DOWELL SCHLUMBERGER INC (US) 1997-01-15 EP disclosed
EP-0669844-A1 VISCOELASTIC SURFACTANT BASED FOAM FLUIDS DOWELL SCHLUMBERGER INCORPORATED (US) 1995-09-06 EP disclosed
WO-1994009852-A1 VISCOELASTIC SURFACTANT BASED FOAM FLUIDS THE DOW CHEMICAL COMPANY (US) 1994-05-11 WO disclosed
US-5258137-A MIXTURE OF SURFACTANT THICKENER, A SURFACTANT CAPABLE OF FORMING A FOAM AND AN AQUEOUS LIQUID THE DOW CHEMICAL COMPANY (US) 1993-11-02 US disclosed
US-4880565-A CATIONIC OR NONIONIC SURFACTANTS ANTIMISTING THE DOW CHEMICAL COMPANY (US) 1989-11-14 US disclosed
US-4770814-A Shear stable antimisting formulations THE DOW CHEMICAL COMPANY (US) 1988-09-13 US disclosed
US-4735731-A ADDING MISCIBLE OR IMMISCIBLE HYDROCARBON THE DOW CHEMICAL COMPANY (US) 1988-04-05 US disclosed
EP-0092581-B1 FRICTION REDUCTION USING A VISCOELASTIC SURFACTANT THE DOW CHEMICAL COMPANY (US) 1986-10-22 EP disclosed
US-4615825-A FOR FLOWING AQUEOUS LIQUIDS THE DOW CHEMICAL COMPANY (US) 1986-10-07 US disclosed
US-4534875-A REACTION PRODUCT OF HYDROPHOBIC HYDROPHILIC SURFACTANT AND ELECTROLYTE THE DOW CHEMICAL COMPANY (US) 1985-08-13 US disclosed
WO-1985003083-A1 A METHOD FOR CONTROLLING THE OVERALL HEAT TRANSFER COEFFICIENT OF A HEAT EXCHANGE FLUID THE DOW CHEMICAL COMPANY (US) 1985-07-18 WO disclosed
EP-0092581-A4 FRICTION REDUCTION USING A VISCOELASTIC SURFACTANT. DOW CHEMICAL CO (US) 1984-03-29 EP disclosed
EP-0092581-A1 FRICTION REDUCTION USING A VISCOELASTIC SURFACTANT. DOW CHEMICAL CO (US) 1983-11-02 EP disclosed
WO-1983001583-A1 FRICTION REDUCTION USING A VISCOELASTIC SURFACTANT DOW CHEMICAL CO (US) 1983-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230090609-A1 Efficient Process For Making 6-Carboxy Benzoxazole Derivatives CYP2B6, CYP4X1, CYP2C9 TPMT 3158/4885HCAR1 118/4885RXRA 249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.