SCHEMBL23699

SCHEMBL23699

O=C(O)c1cc(Cl)cc(Cl)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 3/20 1.00
HCAR1 Q9BXC0 1/20 0.73
RXRA P19793 2/20 0.60
RXRB P28702 2/20 0.60
TTR P02766 1/20 0.56
HCAR2 Q8TDS4 1/20 0.56
TSHR P16473 5/20 0.55
ALOX15 P16050 2/20 0.55
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
SRD5A2 P31213 1/20 0.48
TP53 P04637 2/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
CA3 P07451 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28214359 1.00 TPMT (1.00) TPMTHCAR1RXRARXRBTTR
Bromide SCHEMBL27041421 0.97 TPMT (0.94) TPMTHCAR1RXRARXRBTTR
Iodide SCHEMBL27041428 0.97 TPMT (0.94) TPMTHCAR1RXRARXRBTTR
SCHEMBL8023966 0.97 TPMT (0.94) TPMTHCAR1RXRARXRBTTR
Hydrochloric Acid SCHEMBL10387707 0.97 TPMT (0.94) TPMTHCAR1RXRARXRBTTR
SCHEMBL69625 0.94 TPMT (0.89) TPMTHCAR1RXRARXRBTTR
Hydrochloric Acid SCHEMBL11742420 0.92 TPMT (0.84) TPMTHCAR1RXRARXRBTTR
Hydrochloric Acid SCHEMBL3358926 0.92 TPMT (0.84) TPMTHCAR1RXRARXRBTTR
SCHEMBL28267562 0.90 TPMT (0.81) TPMTHCAR1RXRARXRBTTR
Terephthalic Acid SCHEMBL11195049 0.87 TPMT (0.76) TPMTHCAR1RXRARXRBTTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1940 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4077287-B1 EFFICIENT PROCESS FOR MAKING 6-CARBOXY BENZOXAZOLE DERIVATIVES PFIZER IRELAND PHARMACEUTICALS UNLIMITED COMPANY (IE) 2025-11-19 EP claimed
WO-2025202864-A1 ENT1 INHIBITORS IN COMBINATION WITH ONCOLYTIC VIRUSES AND THEIR USE IN THE TREATMENT OF CANCER iTeos Belgium SA (BE) 2025-10-02 WO claimed
US-20250214921-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND KAO CORPORATION (JP) 2025-07-03 US claimed
WO-2025126110-A1 ENT1 INHIBITORS IN COMBINATION WITH BISPECIFIC ANTIBODIES iTeos Belgium SA (BE) 2025-06-19 WO claimed
WO-2025104613-A1 ENT1 INHIBITORS IN COMBINATION WITH CHECKPOINT INHIBITORS iTeos Belgium SA (BE) 2025-05-22 WO claimed
CN-115135639-B Efficient process for preparing 6-carboxybenzoxazole derivatives 辉瑞爱尔兰制药公司 2025-04-01 CN claimed
CN-119707660-A Method for synthesizing 3, 5-dichlorobenzoic acid 山东兴元倍合德化工有限公司 2025-03-28 CN claimed
CN-119410626-A Magnetic nitrilase catalyst for green cyclic synthesis of organic acid, preparation method and application thereof 浙江工业大学 2025-02-11 CN claimed
EP-4501896-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND Kao Corporation (JP) 2025-02-05 EP claimed
CN-114907283-B Preparation method of 2- (3, 5-dichlorophenyl) -benzoxazole-6-carboxylic acid 南京正大天晴制药有限公司 2025-01-28 CN claimed
EP-0211546-B1 ANALOG ENRICHMENT DECONTAMINATION PROCESS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1988-12-14 EP claimed
US-4735731-A ADDING MISCIBLE OR IMMISCIBLE HYDROCARBON THE DOW CHEMICAL COMPANY (US) 1988-04-05 US claimed
US-4686302-A Simultaneous preparation of nitriles and acrylamide or methacrylamide BASF AKTIENGESELLSCHAFT (DE) 1987-08-11 US claimed
US-4664805-A Analog enrichment decontamination process REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1987-05-12 US claimed
EP-0111608-B1 PSEUDOTROPYL HALOGENO-BENZOATES AND THEIR USE IN MIGRAINE TREATMENT MERRELL TORAUDE ET COMPAGNIE (FR) 1987-03-11 EP claimed
EP-0211546-A1 Analog enrichment decontamination process THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1987-02-25 EP claimed
EP-0079144-B1 PROCESS FOR PRODUCING AROMATIC SULFIDE POLYMERS KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-01-29 EP claimed
US-4451640-A Process for producing aromatic sulfide polymer KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-05-29 US claimed
EP-0079144-A1 Process for producing aromatic sulfide polymers KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1983-05-18 EP claimed
US-4152160-A PHOTOTHERMOGRAPHY, SILVER BEHENATE FUJI PHOTO FILM CO., LTD. (JP) 1979-05-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214921-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND HSD17B7, HSD17B12, BCKDK TPMT 2579/4885HCAR1 3593/4885RXRA 3816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.