Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10860629 | 0.73 | GPR3 (0.41) | GPR3MEN1KMT2ANOX1CA12 | |
| SCHEMBL11633944 | 0.73 | GPR3 (0.41) | GPR3MEN1KMT2ANOX1CA12 | |
| SCHEMBL11638030 | 0.73 | GPR3 (0.41) | GPR3MEN1KMT2ANOX1CA12 | |
| SCHEMBL308829 | 0.73 | GPR3 (0.41) | GPR3MEN1KMT2ANOX1CA12 | |
| SCHEMBL30430615 | 0.73 | GPR3 (0.41) | GPR3MEN1KMT2ANOX1CA12 | |
| SCHEMBL308828 | 0.73 | GPR3 (0.41) | GPR3MEN1KMT2ANOX1CA12 | |
| SCHEMBL8028149 | 0.71 | CA1 (0.39) | GPR3MEN1KMT2ANOX1CA12 | |
| SCHEMBL7526631 | 0.71 | MEN1 (0.43) | GPR3MEN1KMT2ANOX1LMNA | |
| SCHEMBL11036902 | 0.70 | GPR3 (0.55) | GPR3MEN1KMT2ANOX1CA12 | |
| SCHEMBL8664571 | 0.70 | CYP3A4 (0.32) | CASP1CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698474-A | Alpha-substituted tetrahydro-gamma-carboline compound and preparation method and application thereof | 福州大学 | 2020-01-17 | — | — | CN | claimed |
| CN-110698474-B | Alpha-substituted tetrahydro-gamma-carboline compound and preparation method and application thereof | 福州大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-110698474-A | Alpha-substituted tetrahydro-gamma-carboline compound and preparation method and application thereof | 福州大学 | 2020-01-17 | — | — | CN | disclosed |
| WO-2000063202-A2 | BENZO[b] THIOPHENE SULFONAMIDE-1, 1-DIOXIDE DERIVATIVES AND THEIR USE AS ANTINEOPLASTIC AGENTS | UNIVERSIDAD PUBLICA DE NAVARRA (ES) | 2000-10-26 | — | — | WO | disclosed |