Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6656408 | 1.00 | HPGD (0.48) | HPGDALDH1A1TSHRSMN1; SMN2HTT | |
| SCHEMBL4261203 | 1.00 | HPGD (0.48) | HPGDALDH1A1TSHRSMN1; SMN2HTT | |
| SCHEMBL4840663 | 0.98 | HPGD (0.45) | HPGDALDH1A1TSHR | |
| SCHEMBL6695180 | 0.96 | HPGD (0.48) | HPGDTSHR | |
| SCHEMBL11889660 | 0.91 | HPGD (0.41) | HPGD | |
| SCHEMBL7272714 | 0.86 | MAPK1 (0.41) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL10757165 | 0.80 | LMNA (0.41) | HPGDSMN1; SMN2HTT | |
| SCHEMBL8485143 | 0.79 | HRH3 (0.46) | ALDH1A1 | |
| SCHEMBL1661629 | 0.79 | LMNA (0.38) | ALDH1A1HTT | |
| SCHEMBL3999542 | 0.77 | GAA (0.33) | HPGDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706532-B1 | Peptides having endothelin antagonictic activity,their preparation and pharmaceutical compositions | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-02-02 | — | — | EP | disclosed |