Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024241 | 1.00 | NOTUM (0.41) | NOTUML3MBTL1HDAC8KMT2AMEN1 | |
| SCHEMBL8026649 | 0.90 | NOTUM (0.42) | NOTUML3MBTL1HDAC8KMT2AMEN1 | |
| SCHEMBL8026643 | 0.87 | NOTUM (0.40) | NOTUML3MBTL1HDAC8KMT2AMEN1 | |
| SCHEMBL8026645 | 0.87 | NOTUM (0.40) | NOTUML3MBTL1HDAC8KMT2AMEN1 | |
| SCHEMBL29877605 | 0.81 | SMN1; SMN2 (0.37) | NOTUMKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL21858354 | 0.81 | SMN1; SMN2 (0.37) | NOTUMKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL22855341 | 0.79 | GAA (0.35) | NOTUMKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL31432791 | 0.78 | AR (0.41) | LMNA | |
| SCHEMBL8023037 | 0.77 | PPARG (0.48) | L3MBTL1RAB9A | |
| SCHEMBL8023039 | 0.77 | PPARG (0.48) | L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975587-A1 | OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998043949-A1 | OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-10-08 | — | — | WO | disclosed |