Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29877605 | 0.80 | SMN1; SMN2 (0.37) | ACHEKMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21858354 | 0.80 | SMN1; SMN2 (0.37) | ACHEKMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8024245 | 0.79 | NOTUM (0.41) | ACHEKMT2AKDM4EALDH1A1RAB9A | |
| SCHEMBL8024241 | 0.79 | NOTUM (0.41) | ACHEKMT2AKDM4EALDH1A1RAB9A | |
| SCHEMBL31432791 | 0.77 | AR (0.41) | — | |
| SCHEMBL29106882 | 0.74 | PDE4B (0.39) | — | |
| SCHEMBL29890735 | 0.74 | PDE4B (0.39) | — | |
| SCHEMBL30598396 | 0.74 | PDE4B (0.39) | — | |
| SCHEMBL29891091 | 0.73 | PDE4B (0.38) | TDP1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL27082810 | 0.73 | PDE4B (0.38) | TDP1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020262648-A1 | ACRYLIC ESTER DERIVATIVE, AND APPLICATION AND PRODUCTION INTERMEDIATE THEREOF | 住友化学株式会社 | 2020-12-30 | — | — | WO | disclosed |