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Ethylene Glycol

Ethylene Glycol

SCHEMBL8024274

C=C.C=C.C=C.C=C.C=C.C=C.C=C.CCCCCCCCCc1ccc(O)c(Oc2cc(CCCCCCCCC)ccc2O)c1.OCCO

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ KAT8 Q9H7Z6 2/20 0.51
▸ CYP1A2 P05177 1/20 0.51
▸ CYP3A4 P08684 1/20 0.51
▸ CYP2C8 P10632 1/20 0.51
▸ CYP2C9 P11712 1/20 0.51
▸ CYP2B6 P20813 1/20 0.51
▸ CYP2C19 P33261 1/20 0.51
▸ HTR1A P08908 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9008218 0.92 KAT8 (0.58) KAT8CYP1A2CYP3A4CYP2C8CYP2C9
SCHEMBL30192250 0.85 — —
SCHEMBL28234392 0.81 HTR1A (0.72) CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6
SCHEMBL7246840 0.81 HTR1A (0.72) CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6
SCHEMBL6923070 0.81 HTR1A (0.72) CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6
SCHEMBL16609989 0.81 HTR1A (0.72) CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6
SCHEMBL9485313 0.81 HTR1A (0.72) CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6
SCHEMBL7785545 0.80 SMPD1 (0.56) KAT8CYP1A2CYP3A4CYP2C8CYP2C9
SCHEMBL7777461 0.80 SMPD1 (0.56) KAT8CYP1A2CYP3A4CYP2C8CYP2C9
SCHEMBL7785540 0.80 SMPD1 (0.56) KAT8CYP1A2CYP3A4CYP2C8CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6123755-A DOES NOT ELUTE ANTIFOULING COMPOUNDS, DURABLE NIPPON PAINT CO., LTD. (JP) 2000-09-26 — — US disclosed