SCHEMBL8024275

SCHEMBL8024275

CCCCCCCCCc1ccc(O)c(OCCOCCOCCOCCOCCOCCOCCO)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.65
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
USP2 O75604 1/20 0.65
ALDH1A1 P00352 1/20 0.65
LMNA P02545 1/20 0.65
MAPK1 P28482 1/20 0.65
CASP1 P29466 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
SLCO1B3 Q9NPD5 1/20 0.65
SLCO1B1 Q9Y6L6 1/20 0.65
CYP1A2 P05177 1/20 0.47
CYP2C8 P10632 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2B6 P20813 1/20 0.47
CYP2C19 P33261 1/20 0.47
HTR1A P08908 1/20 0.47
KAT8 Q9H7Z6 2/20 0.47
SMPD1 P17405 1/20 0.45
THRB P10828 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7785540 0.87 SMPD1 (0.56) CYP3A4ALDH1A1LMNACYP1A2CYP2C8
SCHEMBL7785545 0.87 SMPD1 (0.56) CYP3A4ALDH1A1LMNACYP1A2CYP2C8
SCHEMBL7777461 0.87 SMPD1 (0.56) CYP3A4ALDH1A1LMNACYP1A2CYP2C8
SCHEMBL7784173 0.87 SMPD1 (0.56) CYP3A4ALDH1A1LMNACYP1A2CYP2C8
SCHEMBL29675018 0.84 MEN1 (0.65) CYP3A4MEN1KMT2AUSP2ALDH1A1
SCHEMBL15929473 0.82 MEN1 (0.58) CYP3A4MEN1KMT2AUSP2ALDH1A1
SCHEMBL6928257 0.82 ALDH1A1 (0.58) CYP3A4MEN1KMT2AUSP2ALDH1A1
SCHEMBL12798635 0.80 MEN1 (0.63) CYP3A4MEN1KMT2AUSP2ALDH1A1
SCHEMBL4245226 0.80 MEN1 (0.54) CYP3A4MEN1KMT2AUSP2ALDH1A1
SCHEMBL20399450 0.80 KAT8 (0.53) CYP3A4ALDH1A1CYP1A2CYP2C8CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6123755-A DOES NOT ELUTE ANTIFOULING COMPOUNDS, DURABLE NIPPON PAINT CO., LTD. (JP) 2000-09-26 US disclosed