Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12984289 | 0.78 | NPC1 (0.50) | KDM4CNPC1RAB9ASMN1; SMN2TLR9 | |
| SCHEMBL23213554 | 0.75 | NPC1 (0.44) | KDM4CNPC1RAB9ASMN1; SMN2TLR9 | |
| SCHEMBL8007356 | 0.72 | NPC1 (0.41) | KDM4CNPC1RAB9ASMN1; SMN2TLR9 | |
| SCHEMBL8024321 | 0.70 | GPR119 (0.46) | SMN1; SMN2ALDH1A1KMT2ATDP1L3MBTL1 | |
| SCHEMBL29488003 | 0.65 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2TLR9TLR8 | |
| SCHEMBL28214905 | 0.65 | NPC1 (0.55) | KDM4CNPC1RAB9ASMN1; SMN2TLR9 | |
| SCHEMBL30071467 | 0.63 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2TLR9TLR8 | |
| SCHEMBL13172364 | 0.63 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL23213584 | 0.63 | POLB (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL17665519 | 0.62 | MEN1 (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000037074-A1 | MUTILIN 14-ESTER DERIVATIVES HAVING ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2000-06-29 | — | — | WO | disclosed |