SCHEMBL8024387

SCHEMBL8024387

CC([O])C(C)C1CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.42
EPHX1 P07099 4/20 0.39
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
MMP2 P08253 2/20 0.38
CA9 Q16790 2/20 0.38
ADH1B P00325 1/20 0.34
ADH1C P00326 1/20 0.34
ADH1A P07327 1/20 0.34
TP53 P04637 1/20 0.33
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8010131 0.97 SHBG (0.38) SHBGEPHX1CA12CA1CA2
SCHEMBL8009630 0.94
SCHEMBL8021879 0.88
SCHEMBL2995478 0.81 SHBG (0.50) SHBGEPHX1CA12CA1CA2
SCHEMBL6673265 0.79 SHBG (0.43) SHBGEPHX1CA12CA1CA2
SCHEMBL1240634 0.79 SHBG (0.43) SHBGEPHX1CA12CA1CA2
SCHEMBL20594356 0.79 SHBG (0.43) SHBGEPHX1CA12CA1CA2
SCHEMBL20594181 0.79 SHBG (0.43) SHBGEPHX1CA12CA1CA2
SCHEMBL21469 0.79
SCHEMBL23595592 0.77 SHBG (0.45) SHBGEPHX1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0971904-A1 NOVEL 1-AMINO-3 BENZYL URACILS BASF AKTIENGESELLSCHAFT (DE) 2000-01-19 EP disclosed
WO-1998042682-A1 NOVEL 1-AMINO-3 BENZYL URACILS BASF AKTIENGESELLSCHAFT (DE) 1998-10-01 WO disclosed