Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14414158 | 0.80 | CYP4F2 (0.44) | CYP4F2CYP4A11APOBEC3GPDCD1CD274 | |
| SCHEMBL29366632 | 0.79 | APOBEC3G (0.60) | CYP4F2CYP4A11APOBEC3GPDCD1CD274 | |
| SCHEMBL41139 | 0.79 | APOBEC3G (0.60) | CYP4F2CYP4A11APOBEC3GPDCD1CD274 | |
| Methylamine SCHEMBL27926648 | 0.78 | CYP4F2 (0.48) | CYP4F2CYP4A11APOBEC3GPDCD1CD274 | |
| SCHEMBL27894267 | 0.77 | SLC6A2 (0.50) | HTR2ATAAR1CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL477605 | 0.77 | CYP4F2 (0.41) | CYP4F2CYP4A11APOBEC3GPDCD1CD274 | |
| SCHEMBL282419 | 0.77 | GABRA1 (0.52) | CYP4F2CYP4A11APOBEC3GPDCD1CD274 | |
| Alanine SCHEMBL8019732 | 0.76 | KMT2A (0.44) | CYP4F2CYP4A11PDCD1CD274LMNA | |
| SCHEMBL477350 | 0.76 | CYP4F2 (0.40) | CYP4F2CYP4A11APOBEC3GPDCD1CD274 | |
| D-Alanine SCHEMBL8021238 | 0.76 | KMT2A (0.44) | CYP4F2CYP4A11PDCD1CD274LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763016-B1 | COMPOSITIONS AND METHODS FOR TREATING MAST-CELL MEDIATED CONDITIONS | AXYS PHARM INC (US) | 2000-01-26 | — | — | EP | disclosed |
| US-5656660-A | AMINE OR GUANIDINE GROUP-CONTAINING TRYPTASE INHIBITOR | ARRIS PHARMACEUTICAL CORPORATION (US) | 1997-08-12 | — | — | US | disclosed |
| EP-0763016-A1 | COMPOSITIONS AND METHODS FOR TREATING MAST-CELL MEDIATED CONDITIONS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995032945-A1 | COMPOSITIONS AND METHODS FOR TREATING MAST-CELL MEDIATED CONDITIONS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1995-12-07 | — | — | WO | disclosed |