Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3785808 | 0.91 | PDE4D (0.52) | ALDH1A1MAPTGAALMNAPDE4D | |
| SCHEMBL7916951 | 0.91 | ALDH1A1 (0.42) | ALDH1A1MAPTGAALMNAPDE4D | |
| Hydrochloric Acid SCHEMBL10318481 | 0.90 | ALDH1A1 (0.42) | ALDH1A1MAPTGAALMNAPDE4D | |
| SCHEMBL8067401 | 0.90 | ALDH1A1 (0.42) | ALDH1A1MAPTGAALMNAPDE4D | |
| SCHEMBL15906192 | 0.89 | MAOB (0.44) | ALDH1A1MAPTGAATSHRMEN1 | |
| SCHEMBL3466486 | 0.88 | PPARG (0.44) | ALDH1A1MAPTGAALMNAPDE4D | |
| SCHEMBL3467033 | 0.88 | MRGPRX4 (0.45) | ALDH1A1MAPTGAALMNATSHR | |
| SCHEMBL3466244 | 0.87 | ERN1 (0.43) | ALDH1A1MAPTGAALMNACYP1A2 | |
| SCHEMBL3467069 | 0.86 | ALDH1A1 (0.38) | ALDH1A1MAPTGAALMNAPDE4D | |
| Hydrochloric Acid SCHEMBL3796887 | 0.86 | SYK (0.41) | ALDH1A1MAPTGAALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067621-A1 | BIARYL PDE4 INHIBITORS FOR TREATING PULMONARY AND CARDIOVASCULAR DISORDERS | DECODE GENETICS EHF (IS) | 2009-05-28 | — | — | WO | disclosed |