SCHEMBL8024477

SCHEMBL8024477

COc1cc(C)[n+](C)c(C)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
CYP3A4 P08684 3/20 0.44
CYP1A1 P04798 6/20 0.40
CYP1B1 Q16678 6/20 0.40
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
CA12 O43570 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CA14 Q9ULX7 2/20 0.38
ACHE P22303 2/20 0.38
CYP1A2 P05177 3/20 0.36
CYP2E1 P05181 2/20 0.36
CYP2C8 P10632 2/20 0.36
CYP2D6 P10635 2/20 0.36
CYP2A6 P11509 2/20 0.36
CYP2C9 P11712 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Perchlorate SCHEMBL7257394 0.91 ALDH1A1 (0.43) ALDH1A1CYP3A4CYP1A1CYP1B1KDM4E
SCHEMBL23555970 0.76 ALDH1A1 (0.50) ALDH1A1CYP3A4CYP1A1CYP1B1KDM4E
1,3,5-Trimethoxybenzene SCHEMBL28493 0.71 ALDH1A1 (1.00) ALDH1A1CYP3A4CYP1A1CYP1B1CA1
SCHEMBL26731120 0.70 ALDH1A1 (0.50) ALDH1A1CYP3A4CYP1A1CYP1B1KDM4E
SCHEMBL5159873 0.69 KDM4E (0.50) ALDH1A1CYP3A4KDM4ETDP1CA1
SCHEMBL2601901 0.69 ALDH1A1 (0.37) ALDH1A1CYP3A4KDM4ETDP1CA1
1,3,5-Trimethoxybenzene SCHEMBL28740008 0.68 ALDH1A1 (0.92) ALDH1A1CYP3A4CYP1A1CYP1B1CA1
1,3,5-Trimethoxybenzene SCHEMBL28416912 0.68 ALDH1A1 (0.92) ALDH1A1CYP3A4CYP1A1CYP1B1CA1
1,3,5-Trimethoxybenzene SCHEMBL28557531 0.68 ALDH1A1 (0.92) ALDH1A1CYP3A4CYP1A1CYP1B1CA1
SCHEMBL7235768 0.67 ALDH1A1 (0.40) ALDH1A1CYP3A4CYP1A1CYP1B1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1056434-A1 DYEING METHOD USING A SPECIFIC CATIONIC DERIVATIVE AND A COMPOUND SELECTED AMONG A SPECIFIC ALDEHYDE, A SPECIFIC KETONE, A QUINONE AND A DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVE L'OREAL (FR) 2000-12-06 EP disclosed
WO-2000038639-A1 DYEING METHOD USING A SPECIFIC CATIONIC DERIVATIVE AND A COMPOUND SELECTED AMONG A SPECIFIC ALDEHYDE, A SPECIFIC KETONE, A QUINONE AND A DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVE L'OREAL (FR) 2000-07-06 WO disclosed