SCHEMBL8024661

SCHEMBL8024661

[O]C(=O)C(CO)Oc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.49
PPARA Q07869 18/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3409853 0.86 PPARG (0.59) PPARGPPARA
SCHEMBL11131627 0.82 ALDH1A1 (0.54) PPARGPPARA
SCHEMBL11059661 0.81 PPARG (0.68) PPARGPPARA
SCHEMBL28391580 0.79 TSHR (0.48) PPARGPPARA
SCHEMBL14288572 0.78 PPARG (0.44) PPARGPPARA
SCHEMBL10735245 0.78 PPARG (0.44) PPARGPPARA
SCHEMBL17724477 0.78 TDP1 (0.50) PPARGPPARA
SCHEMBL11807262 0.78 PPARG (0.44) PPARGPPARA
SCHEMBL17296006 0.78 PPARG (0.44) PPARGPPARA
SCHEMBL11295453 0.75 PSMB5 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0646601-B1 Motilin-like polypeptides with gastrointestinal motor stimulating activity BAXTER INT (US) 2000-07-12 EP disclosed
EP-0647656-B1 Motilin-like polypeptides that inhibit gastrointestinal motor activity BAXTER INT (US) 2000-05-31 EP disclosed
EP-0807639-B1 Cyclic motilin-like polypeptides with gastrointestinal motor stimulating activity BAXTER PHARMACEUTICAL PRODUCTS (US) 2000-02-09 EP disclosed
US-5734012-A Cyclic motilin-like polypeptides with gastrointestinal motor stimulating activity OHMEDA PHARMACEUTICAL PRODUCTS DIVISION INC. (US) 1998-03-31 US disclosed
EP-0807639-A2 Cyclic motilin-like polypeptides with gastrointestinal motor stimulating activity Ohmeda Pharmaceutical Products Division Inc. (US) 1997-11-19 EP disclosed
US-5470830-A Motilin-like polypeptides that inhibit gastrointestinal motor activity OHMEDA PHARMACEUTICAL PRODUCTS DIVISION INC. (US) 1995-11-28 US disclosed
US-5422341-A Antidiabetic agents OHMEDA PHARMACEUTICAL PRODUCTS DIVISION INC. (US) 1995-06-06 US disclosed
EP-0647656-A1 Motilin-like polypeptides that inhibit gastrointestinal motor activity Ohmeda Pharmaceutical Products Division Inc. (US) 1995-04-12 EP disclosed
EP-0646601-A1 Motilin-like polypeptides with gastrointestinal motor stimulating activity Ohmeda Pharmaceutical Products Division Inc. (US) 1995-04-05 EP disclosed