SCHEMBL8024671

SCHEMBL8024671

CCCCCCCCCCCCc1ccc(-c2ccc(O)c(F)c2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 8/20 0.68
RARA P10276 2/20 0.68
RARG P13631 1/20 0.68
MGLL Q99685 6/20 0.56
FAAH O00519 2/20 0.56
CNR1 P21554 2/20 0.56
ESR1 P03372 2/20 0.54
ADRA2A P08913 2/20 0.54
ADORA3 P0DMS8 2/20 0.54
TACR2 P21452 2/20 0.54
SLC6A2 P23975 2/20 0.54
SLC6A4 P31645 2/20 0.54
SLC6A3 Q01959 2/20 0.54
ALDH1A1 P00352 2/20 0.54
CYP3A4 P08684 2/20 0.54
KDM4E B2RXH2 1/20 0.54
LMNA P02545 1/20 0.54
SHBG P04278 1/20 0.54
TP53 P04637 1/20 0.54
HSPD1 P10809 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25797815 1.00 RARB (0.68) RARBRARARARGMGLLFAAH
SCHEMBL10455852 1.00 RARB (0.68) RARBRARARARGMGLLFAAH
SCHEMBL9775756 0.98 RARB (0.65) RARBRARARARGMGLLFAAH
SCHEMBL19722373 0.91 RARB (0.58) RARBRARARARGMGLLFAAH
SCHEMBL9641042 0.87 KAT8 (0.59) RARBRARARARGESR1ADRA2A
SCHEMBL10343322 0.87 KAT8 (0.59) RARBRARARARGESR1ADRA2A
SCHEMBL10435290 0.87 MCL1 (0.59) RARBRARARARGMGLLFAAH
SCHEMBL15725360 0.87 RARB (0.52) RARBRARARARGMGLLFAAH
SCHEMBL9740614 0.87 MAPT (0.54) RARBRARARARGMGLLFAAH
SCHEMBL6250464 0.87 MAPT (0.54) RARBRARARARGMGLLFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6146547-A USEFUL AS COMPONENT OF FERROELECTRIC LIQUID CRYSTAL FORMULATIONS CHISSO CORPORATION (JP) 2000-11-14 US disclosed
EP-0278665-B1 2-Substituted-alkyl ether and liquid crystal composition CHISSO CORP (JP) 1994-09-21 EP disclosed
EP-0277815-B1 Optically active-2-alkoxy-propyl ether and liquid crystal composition CHISSO CORP (JP) 1993-11-24 EP disclosed
US-5120468-A Optical active mixture exhibiting ferroelectricity CHISSO CORPORATION (JP) 1992-06-09 US disclosed
US-5021191-A Ferroelectricity display elements; extremely small redution in crystal temperature region CHISSO CORPORATION (JP) 1991-06-04 US disclosed
EP-0278665-A2 2-Substituted-alkyl ether and liquid crystal composition Chisso Corporation (JP) 1988-08-17 EP disclosed