Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.65 |
| ▸ | RARA | P10276 | 2/20 | 0.65 |
| ▸ | RARG | P13631 | 1/20 | 0.65 |
| ▸ | MGLL | Q99685 | 6/20 | 0.53 |
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | TACR2 | P21452 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25797815 | 0.98 | RARB (0.68) | RARBRARARARGMGLLFAAH | |
| SCHEMBL8024671 | 0.98 | RARB (0.68) | RARBRARARARGMGLLFAAH | |
| SCHEMBL10455852 | 0.98 | RARB (0.68) | RARBRARARARGMGLLFAAH | |
| SCHEMBL19722373 | 0.93 | RARB (0.58) | RARBRARARARGMGLLFAAH | |
| SCHEMBL10435290 | 0.88 | MCL1 (0.59) | RARBRARARARGMGLLFAAH | |
| SCHEMBL15725360 | 0.88 | RARB (0.52) | RARBRARARARGMGLLFAAH | |
| SCHEMBL9313970 | 0.86 | KAT8 (0.57) | CYP3A4ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL6250464 | 0.85 | MAPT (0.54) | RARBRARARARGMGLLFAAH | |
| SCHEMBL9740614 | 0.85 | MAPT (0.54) | RARBRARARARGMGLLFAAH | |
| SCHEMBL6249433 | 0.85 | MAPT (0.54) | RARBRARARARGMGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257839-B1 | POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORP (JP) | 2019-09-04 | — | — | EP | disclosed |
| US-8906260-B2 | Difluoroethyleneoxi derivatives, the liquid crystal composition and the liquid crystal display device | JNC CORPORATION (JP) | 2014-12-09 | — | — | US | disclosed |
| US-8906260-B2 | Difluoroethyleneoxi derivatives, the liquid crystal composition and the liquid crystal display device | JNC CORPORATION (JP) | 2014-12-09 | — | — | US | disclosed |
| US-20130230669-A1 | DIFLUOROETHYLENEOXI DERIVATIVES, THE LIQUID CRYSTAL COMPOSITION AND THE LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2013-09-05 | — | — | US | disclosed |
| US-20130230669-A1 | DIFLUOROETHYLENEOXI DERIVATIVES, THE LIQUID CRYSTAL COMPOSITION AND THE LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2013-09-05 | — | — | US | disclosed |
| US-5047170-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1991-09-10 | — | — | US | disclosed |
| US-4808333-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1989-02-28 | — | — | US | disclosed |