Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.67 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.67 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.67 |
| ▸ | MET | P08581 | 1/20 | 0.67 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.67 |
| ▸ | FLT1 | P17948 | 1/20 | 0.67 |
| ▸ | LTK | P29376 | 1/20 | 0.67 |
| ▸ | GRK5 | P34947 | 1/20 | 0.67 |
| ▸ | CDK8 | P49336 | 1/20 | 0.67 |
| ▸ | PRKX | P51817 | 1/20 | 0.67 |
| ▸ | NEK2 | P51955 | 1/20 | 0.67 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.67 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.67 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.67 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.67 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.67 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.67 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.67 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.67 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059384 | 0.84 | CHEK1 (0.51) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL8040661 | 0.82 | CHEK1 (0.75) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL8034425 | 0.81 | ADORA3 (0.61) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL8040672 | 0.80 | CHEK1 (1.00) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL8040469 | 0.80 | CHEK1 (0.69) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL8558992 | 0.80 | CHEK1 (0.44) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL8024616 | 0.80 | ADORA3 (0.67) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL8553189 | 0.80 | CHEK1 (0.43) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL8554080 | 0.78 | CHEK1 (0.49) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL11371536 | 0.78 | MAPT (0.48) | CHEK1DAPK3PRKD3METPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121265-A | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |