Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 5/20 | 0.68 |
| ▸ | LTA4H | P09960 | 1/20 | 0.64 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.60 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.50 |
| ▸ | RXRA | P19793 | 3/20 | 0.50 |
| ▸ | RXRB | P28702 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL28453225 | 0.87 | TSHR (0.63) | SRD5A2SMN1; SMN2TSHRCA1CA2 | |
| Terephthalic Acid SCHEMBL28358133 | 0.87 | TSHR (0.63) | SRD5A2SMN1; SMN2TSHRCA1CA2 | |
| SCHEMBL49984 | 0.87 | TSHR (0.63) | SRD5A2SMN1; SMN2TSHRCA1CA2 | |
| SCHEMBL5581537 | 0.86 | SRD5A2 (0.89) | SRD5A2PARP15PARP10SMN1; SMN2NR4A2 | |
| SCHEMBL9243055 | 0.86 | SRD5A2 (0.70) | SRD5A2PARP15PARP10SMN1; SMN2NR4A2 | |
| Ethylene Glycol SCHEMBL11410880 | 0.85 | PARP10 (0.67) | SRD5A2PARP15PARP10TSHRNR4A2 | |
| SCHEMBL10570096 | 0.85 | TSHR (0.60) | SRD5A2SMN1; SMN2TSHRCA1CA2 | |
| Ammonia Solution, Strong SCHEMBL11061336 | 0.85 | TSHR (0.60) | SRD5A2SMN1; SMN2TSHRCA1CA2 | |
| SCHEMBL15251986 | 0.85 | TSHR (0.60) | SRD5A2SMN1; SMN2TSHRCA1CA2 | |
| SCHEMBL766069 | 0.85 | PARP10 (0.78) | SRD5A2PARP15PARP10TSHRRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071504-A1 | 2,6-DISUBSTITUTED PYRIDINES AS SOLUBLE GUANYLATE CYCLASE ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-11 | — | — | WO | disclosed |