SCHEMBL49984

SCHEMBL49984

O=C(O)c1ccc(CO)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.63
TP53 P04637 1/20 0.63
ALDH1A1 P00352 4/20 0.62
SRD5A2 P31213 2/20 0.55
SMN1; SMN2 Q16637 4/20 0.53
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA12 O43570 1/20 0.52
CA3 P07451 1/20 0.52
TYR P14679 1/20 0.52
DRD1 P21728 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA5A P35218 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
CA5B Q9Y2D0 1/20 0.52
KMT2A Q03164 2/20 0.52
NPC1 O15118 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL28453225 1.00 TSHR (0.63) TSHRTP53ALDH1A1SRD5A2SMN1; SMN2
Terephthalic Acid SCHEMBL28358133 1.00 TSHR (0.63) TSHRTP53ALDH1A1SRD5A2SMN1; SMN2
SCHEMBL10570096 0.97 TSHR (0.60) TSHRTP53ALDH1A1SRD5A2SMN1; SMN2
Ammonia Solution, Strong SCHEMBL11061336 0.97 TSHR (0.60) TSHRTP53ALDH1A1SRD5A2SMN1; SMN2
SCHEMBL15251986 0.97 TSHR (0.60) TSHRTP53ALDH1A1SRD5A2SMN1; SMN2
SCHEMBL27686277 0.93 ALDH1A1 (0.56) TSHRTP53ALDH1A1SRD5A2SMN1; SMN2
SCHEMBL3641834 0.93 RARB (0.58) TSHRTP53ALDH1A1SRD5A2CA1
Cyclopropane SCHEMBL8984335 0.93 ALDH1A1 (0.56) TSHRTP53ALDH1A1SRD5A2SMN1; SMN2
Benzoic Acid SCHEMBL5085720 0.90 TSHR (0.67) TSHRTP53ALDH1A1SRD5A2SMN1; SMN2
Terephthalic Acid SCHEMBL6473290 0.89 ALDH1A1 (0.71) TSHRTP53ALDH1A1SRD5A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3511 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
CN-115974758-B Carboxymethyl ketone compound and preparation method thereof 生物岛实验室 2025-06-10 CN claimed
CN-119841727-A Method for directly preparing carboxylic ester compound from aromatic aldehyde, ketone and carboxylic acid 湖南第一师范学院 2025-04-18 CN claimed
CN-119776944-A Biochip, preparation method and application thereof 深圳华大生命科学研究院 2025-04-08 CN claimed
WO-2025057535-A1 SEPARATION MEMBRANE 日東電工株式会社 2025-03-20 WO claimed
CN-119505692-A High-temperature-resistant insulating paint and preparation method and application thereof 湖南华菱线缆股份有限公司 2025-02-25 CN claimed
CN-119039384-A Preparation method of leuprorelin impurity K 深圳市健元医药科技有限公司 2024-11-29 CN claimed
CN-119039383-A Preparation method of leuprorelin impurity K 深圳市健元医药科技有限公司 2024-11-29 CN claimed
CN-117843276-B Multi-component composite steel slag grinding-aid excitant and preparation method thereof 华新水泥股份有限公司 2024-11-26 CN claimed
CN-118994027-A Imidazole-containing long-chain cross-linking agent, high-temperature proton exchange membrane and preparation method thereof 上海空间电源研究所 2024-11-22 CN claimed
US-4528361-A Copolymers of hydroxymethylbenzoic acid and lactam STANDARD OIL COMPANY (INDIANA) (US) 1985-07-09 US claimed
US-4457814-A TO P-HYDROXYMETHYLBENZOIC ACID STANDARD OIL COMPANY (INDIANA) (US) 1984-07-03 US claimed
US-4448987-A Catalyzed hydrogenation of terephthalic acid to p-hydroxymethylbenzoic acid using a rhenium catalyst STANDARD OIL COMPANY (INDIANA) (US) 1984-05-15 US claimed
US-4447645-A HYDROGENATION OF 4-CARBOXYLBENZALDEHYDE, SEPARATION, FILTRATION, HYDROCARBON EXTRACTION OF P-TOLUIC ACID, AND CRYSTALLIZATION STANDARD OIL COMPANY (INDIANA) (US) 1984-05-08 US claimed
US-4431798-A CATALYTIC MELT POLYMERIZATION WITH IMPURITIES OF TEREPHTHALIC ACID, P-CARBOXYBENZALDEHYDE AND P-TOLUIC ACID STANDARD OIL COMPANY (INDIANA) (US) 1984-02-14 US claimed
US-4431797-A ELECTROLYTIC REDUCTION OF TEREPHTHALIC ACID TO AMMONIUM SALT OF P- STANDARD OIL COMPANY (INDIANA) (US) 1984-02-14 US claimed
US-4402805-A REDUCTION OF TEREPHTHALIC ACID STANDARD OIL COMPANY INDIANA (US) 1983-09-06 US claimed
EP-0081611-A1 Process for electrochemical reduction of terephthalic acid AMOCO CORPORATION (US) 1983-06-22 EP claimed
US-4381229-A Process for electrochemical reduction of terephthalic acid STANDARD OIL COMPANY (INDIANA) (US) 1983-04-26 US claimed
US-4182847-A Monomers for poly(methylenebenzoate) polymers from toluic acid compounds STANDARD OIL COMPANY (INDIANA) (US) 1980-01-08 US claimed