Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | MMP16 | P51512 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3036255 | 0.77 | CXCL8 (0.56) | CXCL8L3MBTL1AKR1B1CHRM1PTGER1 | |
| SCHEMBL29431297 | 0.77 | HSD17B10 (0.61) | CXCL8L3MBTL1AKR1B1MEN1POLB | |
| SCHEMBL155982 | 0.77 | HSD17B10 (0.61) | CXCL8L3MBTL1AKR1B1MEN1POLB | |
| SCHEMBL12986104 | 0.76 | CXCL8 (0.54) | CXCL8L3MBTL1AKR1B1CHRM1PTGER1 | |
| Hydrochloric Acid SCHEMBL2527513 | 0.75 | HSD17B10 (0.59) | CXCL8L3MBTL1AKR1B1MEN1POLB | |
| SCHEMBL28215186 | 0.75 | HSD17B10 (0.59) | CXCL8L3MBTL1AKR1B1MEN1POLB | |
| SCHEMBL8416291 | 0.75 | AKR1B1 (0.46) | CXCL8L3MBTL1AKR1B1MEN1KMT2A | |
| SCHEMBL9016420 | 0.75 | AKR1B1 (0.46) | CXCL8L3MBTL1AKR1B1MEN1KMT2A | |
| SCHEMBL8343067 | 0.75 | AKR1B1 (0.46) | CXCL8L3MBTL1AKR1B1MEN1KMT2A | |
| SCHEMBL10973471 | 0.74 | CXCL8 (0.49) | CXCL8L3MBTL1AKR1B1CHRM1CAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675133-B1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO CO (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5614470-A | AGRICULTURAL ANTHELMINTIC, ACARICIDE, INSECTICIDE | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0675133-A1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1995-10-04 | — | — | EP | disclosed |