Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034605 | 0.74 | CYP1A2 (0.41) | GAAGRIN2DGRIN1GRIN2AGRIN2B | |
| SCHEMBL13740317 | 0.66 | CHRM3 (0.58) | GAASMN1; SMN2GRIN2DGRIN1GRIN2A | |
| SCHEMBL28564931 | 0.65 | CYP2D6 (0.48) | GAASMN1; SMN2GRIN2DGRIN1GRIN2A | |
| SCHEMBL3652874 | 0.65 | CYP2D6 (0.48) | GAASMN1; SMN2GRIN2DGRIN1GRIN2A | |
| SCHEMBL21273795 | 0.65 | CYP1A2 (0.48) | GAASMN1; SMN2GRIN2DGRIN1GRIN2A | |
| SCHEMBL1394341 | 0.65 | CYP1A2 (0.48) | GAASMN1; SMN2GRIN2DGRIN1GRIN2A | |
| SCHEMBL3862385 | 0.65 | CYP2C19 (0.43) | GAASMN1; SMN2GRIN2DGRIN1GRIN2A | |
| SCHEMBL15598278 | 0.65 | GAA (0.44) | GAASMN1; SMN2GRIN2DGRIN1GRIN2A | |
| SCHEMBL3018220 | 0.64 | CYP2C19 (0.42) | SMN1; SMN2CYP2D6CYP1A2MAPTKIF11 | |
| SCHEMBL16732258 | 0.64 | KCNN4 (0.55) | GAASMN1; SMN2GRIN2DGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020518-A | Process for preparing β-amino-α-hydroxy acid derivatives | KANEKA CORPORATION (JP) | 2000-02-01 | — | — | US | disclosed |