Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.77 |
| ▸ | NPC1 | O15118 | 2/20 | 0.77 |
| ▸ | CASP3 | P42574 | 1/20 | 0.77 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.77 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.77 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | CNR2 | P34972 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021524 | 1.00 | RAB9A (0.77) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL8025204 | 0.99 | RAB9A (0.78) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL7675932 | 0.90 | MEN1 (0.81) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL8025190 | 0.89 | KMT2A (0.65) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL15954070 | 0.88 | RAB9A (0.77) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL22516308 | 0.85 | MAPT (0.76) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL7658611 | 0.84 | RAB9A (0.66) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL22501551 | 0.84 | MAPT (0.71) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL22516014 | 0.84 | MAPT (0.77) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL7666105 | 0.83 | RAB9A (0.65) | RAB9ANPC1CASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | disclosed |