Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.55 |
| ▸ | DRD2 | P14416 | 5/20 | 0.55 |
| ▸ | DRD3 | P35462 | 5/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.55 |
| ▸ | HTR2C | P28335 | 3/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.55 |
| ▸ | HRH1 | P35367 | 3/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18350826 | 0.92 | MEN1 (0.51) | HTR2AMAPTMEN1KMT2AKDM4E | |
| SCHEMBL6419291 | 0.90 | MEN1 (0.66) | HTR2AMAPTMEN1KMT2AKDM4E | |
| SCHEMBL4920571 | 0.87 | HTR2A (0.65) | HTR2AMAPTMEN1KMT2AKDM4E | |
| SCHEMBL284853 | 0.85 | HDAC3 (0.56) | HTR2AMAPTMEN1KMT2AKDM4E | |
| SCHEMBL7603769 | 0.85 | SLC6A2 (0.58) | HTR2AMAPTMEN1KMT2AKDM4E | |
| SCHEMBL4733904 | 0.84 | SLC6A4 (0.65) | HTR2AMAPTMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL7810034 | 0.84 | SLC6A2 (0.59) | HTR2AMAPTMEN1KMT2AKDM4E | |
| Desipramine SCHEMBL9485122 | 0.83 | SLC6A2 (0.71) | HTR2AMAPTMEN1KMT2AKDM4E | |
| SCHEMBL13051501 | 0.82 | HTR2A (0.78) | HTR2AMAPTMEN1KMT2AKDM4E | |
| SCHEMBL18350824 | 0.81 | MEN1 (0.62) | HTR2AMAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000064884-A1 | PIPERIDYL-IMIDAZOLE DERIVATIVES, THEIR PREPARATIONS AND THERAPEUTIC USES | NOVO NORDISK A/S (DK) | 2000-11-02 | — | — | WO | disclosed |