Fructose

Fructose

SCHEMBL8025670

CC(=O)CC(C)C.O=C(CO)[C@H](O)[C@@H](O)[C@H](O)CO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.42
PDE4A P27815 1/20 0.38
LMNA P02545 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.34
USP2 O75604 1/20 0.32
SLCO1B1 Q9Y6L6 1/20 0.32
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fructose SCHEMBL27963851 0.86 CYP2C9 (0.47) TDP1ALDH1A1CYP2C9TSHRPDE4A
Fructose SCHEMBL28094052 0.85 CYP2C9 (0.52) TDP1CYP2C9TSHRPDE4ALMNA
Fructose SCHEMBL28155729 0.85 CYP2C9 (0.52) TDP1CYP2C9TSHRPDE4ALMNA
Fructose SCHEMBL10835862 0.85 CYP2C9 (0.52) TDP1CYP2C9TSHRPDE4ALMNA
Fructose SCHEMBL2638706 0.85 CYP2C9 (0.52) TDP1CYP2C9TSHRPDE4ALMNA
Fructose SCHEMBL28298046 0.85 CYP2C9 (0.52) TDP1CYP2C9TSHRPDE4ALMNA
Fructose SCHEMBL3036243 0.85 CYP2C9 (0.52) TDP1CYP2C9TSHRPDE4ALMNA
Fructose SCHEMBL11432055 0.85 CYP2C9 (0.52) TDP1CYP2C9TSHRPDE4ALMNA
Fructose SCHEMBL8035519 0.83 CYP2C9 (0.47) TDP1ALDH1A1CYP2C9TSHRPDE4A
Fructose SCHEMBL7162293 0.83 CYP2C9 (0.56) TDP1CYP2C9TSHRPDE4ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6096692-A CYLIC KETALS AND ACDTALS HAVING HEAT AND OXIDATION RESISTANCE, ARE FREE FROM CARBOXYLIC ACIDS FORMING DUE TO HYDROLYSIS, LOW IN HYGROSCOPICITY, INEXPENSIVE, GOOD INSULATION AND COMPATIBLE WITH HYDROFLUOROCARBONS; WORKING FLUID REFRIGERANTS KAO CORPORATION (JP) 2000-08-01 US disclosed